H-89 . dihydrochloride
Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Protein kinase Cµ (PKCµ) inhibitor. Ca2+/calmodulin-dependent protein kinase II inhibitor. Casein kinase I inhibitor. Myosin light chain kinase (MLCK) inhibitor. Apoptosis enhancer. Tool to study protein crystal structure-inhibitor interactions. Rho kinase inhibitor. Cell proliferation inhibitor. Review.
| Catalog Number | AG-CR1-0002-M001 |
| Alternative Name(s) | N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide . 2HCl |
| Research Area | Biochemicals, Cancer |
| Molecular Formula | C20H20BrN3O2S . 2HCl |
| CAS# | 130964-39-5 | 127243-85-0 (free base) |
| Purity | >98% |
| Inchi | InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+ |
| Inchi Key | ZKZXNDJNWUTGDK-NSCUHMNNSA-N |
| SMILES | BrC1=CC=C(C=CCNCCNS(=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0002/h-89-dihydrochloride.html |