Antipain . dihydrochloride

Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. Used to evaluate the role of proteases in the process of malignant cell transformations. Shows antibacterial and antiparasitic activity.

Price Not Available 5 mg Antipain . dihydrochloride Supplier Page

Catalog Number	AG-CP3-7002-M005
Alternative Name(s)	[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl
Research Area	Apoptosis, Autophagy, Biochemicals, Cancer, Cell Death, Inflammation, Necrosis, Neurodegenerative Disease
Molecular Formula	C27H44N10O6 . 2HCl
CAS#	37682-72-7
Purity	>97%
Inchi	InChI=1S/C27H44N10O6.2ClH/c1-16(2)21(23(40)34-18(15-38)10-6-12-32-25(28)29)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21H,6-7,10-14H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43);2*1H/t18?,19-,20?,21-;;/m0./s1
Inchi Key	YAHXZYICKJUJEO-BXLPLHKWSA-N
SMILES	[Cl-].[Cl-].[H]C(=O)C(CCCNC(N)=[NH2+])NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)NC(CC1=CC=CC=C1)C(O)=O)C(C)C
Size	5 mg
Supplier Page	http://www.adipogen.com/ag-cp3-7002/antipain-dihydrochloride.html