Ganglioside GQ1b . tetrasodium salt (bovine brain)
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients.
| Catalog Number | AG-CN2-9007-C100 |
| Alternative Name(s) | GQ1b . 4Na; Tetrasialoganglioside GQ1b . 4Na |
| Research Area | Cancer, Inflammation, Natural Products, Neurobiology, Neurodegenerative Disease |
| Molecular Formula | C106H178N6O55 . 4Na |
| CAS# | 68652-37-9 |
| Purity | >98% |
| Inchi | InChI=1S/C106H182N6O55.4Na/c1-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-70(133)112-56(57(126)36-34-32-30-28-26-24-21-19-17-15-13-11-9-2)50-152-96-83(141)82(140)86(68(48-119)155-96)157-98-85(143)94(167-106(102(150)151)41-61(130)74(110-54(6)124)92(165-106)81(139)67(47-118)161-104(100(146)147)39-59(128)72(108-52(4)122)90(163-104)77(135)63(132)43-114)87(69(49-120)156-98)158-95-75(111-55(7)125)88(78(136)64(44-115)153-95)159-97-84(142)93(79(137)65(45-116)154-97)166-105(101(148)149)40-60(129)73(109-53(5)123)91(164-105)80(138)66(46-117)160-103(99(144)145)38-58(127)71(107-51(3)121)89(162-103)76(134)62(131)42-113;;;;/h34,36,56-69,71-98,113-120,126-132,134-143H,8-33,35,37-50H2,1-7H3,(H,107,121)(H,108,122)(H,109,123)(H,110,124)(H,111,125)(H,112,133)(H,144,145)(H,146,147)(H,148,149)(H,150,151);;;;/q;4*+1/p-4/b36-34+;;;;/t56-,57+,58?,59?,60?,61?,62+,63+,64?,65?,66-,67-,68?,69?,71+,72+,73+,74+,75?,76-,77-,78-,79+,80-,81-,82?,83?,84?,85?,86+,87-,88?,89?,90?,91?,92?,93?,94?,95+,96+,97-,98-,103+,104+,105-,106-;;;;/m0../s1 |
| Inchi Key | QISNAVHLOKDTLS-UTKQHEHRSA-J |
| SMILES | [Na+].[Na+].[Na+].[Na+].[H][C@@](O)(CO)[C@]([H])(O)C1O[C@@](CC(O)[C@H]1NC(C)=O)(O[C@@]([H])(CO)[C@]([H])(O)C1O[C@@](CC(O)[C@H]1NC(C)=O)(O[C@H]1[C@H](O)C(CO)O[C@@H](OC2[C@@H](O)[C@H](CO)O[C@H](O[C@H]3C(CO)O[C@@H](O[C@H]4C(O)C(O)[C@H](OC[C@]([H])(NC(=O)CCCCCCCCCCCCCCCCC)[C@]([H])(O)C=CCCCCCCCCCCCCC)O[C@H]4CO)C(O)[C@H]3O[C@@]3(CC(O)[C@@H](NC(C)=O)C(O3)[C@@]([H])(O)[C@]([H])(CO)O[C@@]3(CC(O)[C@@H](NC(C)=O)C(O3)[C@@]([H])(O)[C@]([H])(O)CO)C([O-])=O)C([O-])=O)C2NC(C)=O)C1O)C([O-])=O)C([O-])=O |
| Size | 100 µg |
| Supplier Page | http://www.adipogen.com/ag-cn2-9007/ganglioside-gq1b-tetrasodium-salt.html |