Convulxin

Glycoprotein GPVI receptor agonist. Can be used for studies on platelet receptors. Activates mammalian platelets via binding and clustering of GPVI-receptors under physiological conditions. Occupation and clustering of GPVI activates Src family kinases, phosphorylates Fc receptor gamma-chain and activates p72SYK that is critical for downstream activation of platelets. Causes cardiovascular and respiratory disturbances. Prostaglandins are strong inhibitors of convulxin-induced aggregation. Heterodimeric C-type lectin. Disulfide linked heterodimer consisting of homologous alpha and beta chains. The heterodimers are additionally linked by disulfide bridges to form cyclic alpha(4)beta(4)heterotetramers.

Price Not Available 50 µg Convulxin Supplier Page
Catalog Number AG-CN2-0465-C050
Alternative Name(s) CVX
Research Area Immunology, Natural Products
CAS# 37206-04-5
Size 50 µg
Supplier Page http://www.adipogen.com/ag-cn2-0465/convulxin.html