Meleagrin
Mycotoxin. Alkaloid antibiotic. Bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor. Antineoplastic activity. Moderate cytotoxicity against A-549 and HL-60 cell lines. Induces cell cycle arrest through G2/M phase, presumably by inhibiting tubulin polymerization. Antifouling agent against the barnacle Balanus amphitrite.
| Catalog Number | AG-CN2-0451-M001 |
| Alternative Name(s) | 6-O-Methyloxaline |
| Research Area | Cancer, Cell Death, Natural Products |
| Molecular Formula | C23H23N5O4 |
| CAS# | 71751-77-4 |
| Purity | >90% |
| Inchi | InChI=1S/C23H23N5O4/c1-5-21(2,3)22-11-18(29)20(31)27-17(10-14-12-24-13-25-14)19(30)26-23(22,27)28(32-4)16-9-7-6-8-15(16)22/h5-13,29H,1H2,2-4H3,(H,24,25)(H,26,30)/b17-10+/t22-,23-/m0/s1 |
| Inchi Key | JTJJJLSLKZFEPJ-ZAYCRUKZSA-N |
| SMILES | CON1C2=C(C=CC=C2)[C@@]2(C=C(O)C(=O)N3C(=CC4=CN=CN4)C(=O)N[C@@]123)C(C)(C)C=C |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0451/meleagrin.html |