Manzamine A

Antibiotic. Antibacterial against Gram positive and Gram negative bacteria. Exhibits chemotherapeutic activity. Blocks tumor cell invasion and restores cancer cell susceptibility to apoptosis in vitro. Uncouples vacuolar ATPases, inhibiting autophagy and tumor growth. Antimalaria, antifungal and antiviral agent. GSK-3beta inhibitor. Anti-Alzheimer’s agent. Decreased tau hyperphosphorylation. Anti-hyperlipidemic. Inhibits cholesterol ester formation and acyl-CoA:cholesterol acyl-transferase (ACAT) activity in vitro and decreases total cholesterol, triglycerides and LDL levels. Anti-atherosclerotic. Inhibits foam cell formation in macrophages.

Price Not Available 500 µg Manzamine A Supplier Page

Catalog Number	AG-CN2-0438-C500
Alternative Name(s)	Keramamine A
Research Area	Antibiotic, Immunology, Inflammation, Natural Products
Molecular Formula	C36H44N4O
CAS#	104196-68-1
Purity	>98%
Inchi	InChI=1S/C36H42N4O/c41-36-16-8-3-7-15-34-17-21-39-20-14-28(35(23-34,24-39)33(36)40-19-9-2-1-4-12-30(34)40)27(22-36)31-32-26(13-18-37-31)25-10-5-6-11-29(25)38-32/h3-7,10-13,18,22,28,30,33,38,41H,1-2,8-9,14-17,19-21,23-24H2/b7-3-,12-4-/t28-,30-,33+,34?,35-,36-/m0/s1
Inchi Key	CSJUQSWULVSLGK-ILRBDQACSA-N
SMILES	[H][C@@]12CCN3C[C@@]11CC4(CC3)CC=C/CC[C@](O)(C=C2C2=C3NC5=C(C=CC=C5)C3=CC=N2)[C@]1([H])N1CCCCC=C/[C@@]41[H]
Size	500 µg
Supplier Page	http://www.adipogen.com/ag-cn2-0438/manzamine-a.html