Chenodeoxycholic acid

Cytotoxic hydrophobic primary bile acid. Activator of farnesoid X receptor (FXR), a nuclear receptor that is hepatoprotective and regulates bile acid synthesis (cholesterol 7alpha-hydroxylase (CYP7A1) suppression), conjugation and transport, as well as genes involved in lipid and glucose metabolism and. Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, insulin resistance, hyperlipidemia and atherosclerosis. Inhibitor of 5beta-reductase (AKR1D1). Potent selective inhibitor of DD2 (AKR1C2). Potent inhibitor of 11beta-HSD1 dehydrogenase. Changes tumor cell viability via IL-6 pathway. Anticancer compound. Apoptosis inducer. Immunosuppressive and anti-inflammatory compound. Modulates oxidative stress. Differentiation regulator of mouse embryonic stem cells. Used for dissolution of cholesterol gallstones.

Price Not Available 100 mg Chenodeoxycholic acid Supplier Page

Catalog Number	AG-CN2-0410-M100
Alternative Name(s)	CDCA; Ulmenide; Kebilis; Hekbilin; Fluibil; Chenodiol; Anthropodeoxycholic acid
Research Area	Biochemicals, Cancer, Metabolism, Natural Products, Obesity, Stem Cell Research
Molecular Formula	C24H40O4
CAS#	474-25-9
Purity	>95%
Inchi	InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1
Inchi Key	RUDATBOHQWOJDD-BSWAIDMHSA-N
SMILES	[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O
Size	100 mg
Supplier Page	http://www.adipogen.com/ag-cn2-0410/chenodeoxycholic-acid.html