Lactacystin
Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. beta-Secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.
| Catalog Number | AG-CN2-0104-C500 |
| Research Area | Antibiotic, Apoptosis, Autophagy, Cancer, Cell Death, Inflammation, Metabolism, Natural Products, Neurobiology |
| Molecular Formula | C15H24N2O7S |
| CAS# | 133343-34-7 |
| Purity | >98% |
| Inchi | InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9?,10+,11+,15-/m1/s1 |
| Inchi Key | DAQAKHDKYAWHCG-MJZHQVMOSA-N |
| SMILES | CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O |
| Size | 500 µg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0104/lactacystin.html |