Paclitaxel
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi’s sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK). Immunosuppressor. Immunostimulant. Antiproliferative agent for the prevention of restenosis. TRAIL sensitizer
| Catalog Number | AG-CN2-0045-M005 |
| Alternative Name(s) | Taxol; BMS 181339-01; NSC 125973 |
| Research Area | Apoptosis, Cancer, Cell Death, Immunology, Inflammation, Natural Products |
| Molecular Formula | C47H51NO14 |
| CAS# | 33069-62-4 |
| Purity | >99% |
| Inchi | InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1 |
| Inchi Key | RCINICONZNJXQF-MZXODVADSA-N |
| SMILES | [H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](OC(C)=O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C5=CC=CC=C5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0045/paclitaxel.html |