Hyperforin . DCHA
Key constituent of St. John’s wort. Shows properties of potential pharmacological interest, including antibacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor.
| Catalog Number | AG-CN2-0008-C500 |
| Alternative Name(s) | (1R,5R,6R,7S)-2-Hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione . DCHA |
| Research Area | Cancer, Inflammation, Metabolism, Natural Products |
| Molecular Formula | C35H51O4 . C12H24N |
| CAS# | 238074-03-8 |
| Purity | >97% |
| Inchi | InChI=1S/C35H52O4.C12H23N/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h13-15,18,26-27,38H,12,16-17,19-21H2,1-11H3;11-13H,1-10H2/t27-,33+,34+,35-;/m0./s1 |
| Inchi Key | ZUYCAROZOLUHJY-DNSWOBEMSA-N |
| SMILES | C1CCC(CC1)NC1CCCCC1.CC(C)C(=O)[C@@]12C(O)=C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O |
| Size | 500 µg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0008/hyperforin-dcha.html |