ABT-263 (Navitoclax) 100mg | 98.02%
APEXBIO TECHNOLOGY LLC

Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w Apoptosis|Bcl-2 Family
More Information Supplier PagePotent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w Apoptosis|Bcl-2 Family
More Information Supplier PageA monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid
More Information Supplier PageA monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid
More Information Supplier PageA monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid
More Information Supplier Page(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC50 value of 200 nM.[1]
More Information Supplier Page(±) 5-HETE Lactone is a unique marker for 5-lipoxygenase activation. (±) 5-HETE Lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It inhibits 5-LO (5-lipoxygenase) (IC50=27 µM) from rat basophilic leukemia cells. The lactone form is several times more potent.
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