Bim-BLK-A
Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC). Bim-BLK-A protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction.
Catalog Number | T26817 |
Alternative Name(s) | Bim Blocker A , Compound A , Bim BLK A , BimBLKA |
Molecular Formula | C20H18F3N3O5S |
CAS# | T26817 |
SMILES | O=C1C=CC(C2=NC(S(=O)(C)=O)=NC(C(F)(F)F)=C2)=CN1CC3=CC=C(OC)C(OC)=C3 |
Size | 500 mg |
Supplier Page | https://www.targetmol.com/compound/Bim-BLK-A |
Additional Information | https://www.targetmol.com/datasheet/T26817 |