(±)-AMG 487
AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).
![](https://smallmolecules.com/sm/wp-content/uploads/products/targetmol/cg/cgoadmuaa4cemtbtaaaaafwi2ee200.png)
Catalog Number | T22477 |
Research Area | Others |
Molecular Formula | C32H28F3N5O4 |
CAS# | T22477 |
SMILES | CCOC1=CC=C(N2C(C(N(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC4=CN=CC=C4)C)=NC5=C(C2=O)C=CC=N5)C=C1 |
Size | 10 mg |
Supplier Page | https://www.targetmol.com/compound/(±)-AMG 487 |
Additional Information | https://www.targetmol.com/datasheet/T22477 |