ZX703
ZX703 is a proteolysis targeting chimera (PROTAC), that is a degrader of GPX4 through the ubiquitin-proteasome and the autophagy-lysosome with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby inducing ferroptosis cancer cells.
| Catalog Number | E4652 |
| Molecular Formula | C17H19FN4O2 |
| SMILES | ONC(=O)C1=CN=C(NC2(CCCCC2)C3=CC(=CC=C3)F)N=C1 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/zx703.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4652-ZX703-chemical-structure-tube.png |