Z57346765 hydrochloride

Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP-binding pocket with a KD value of 2.09 × 10⁻⁵ M, reducing PGK1 metabolic enzyme activity, glucose consumption, and lactate production. It also inhibits DNA replication, impairs DNA damage repair, and induces cell cycle arrest in kidney renal clear cell carcinoma (KIRC) cells.

Price Not Available 5mg Z57346765 hydrochloride Supplier Page

Catalog Number	E8275
Molecular Formula	C23H28O11
Inchi	InChI=1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20 +,21+,22-,23+/m1/s1
Inchi Key	YKRGDOXKVOZESV-WRJNSLSBSA-N
SMILES	CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/z57346765-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E8275-Z57346765-hydrochloride-chemical-structure.png