T26
T26( PARP1-IN-35) is a potent, selective, orally active, inhibitor of PARP1 capable of crossing the blood-brain barrier, with IC50 values of 0.2 nM. It exhibits significant antitumor efficacy and holds potential as a research treatment for breast cancer metastases.
| Trivial name | PARP1-IN-35 |
| Catalog Number | E5851 |
| Molecular Formula | C18H14N6O2 |
| Inchi | InChI=1S/C18H14N6O2/c19-16-15-17(24-18(20)23-16)22-14(10-4-2-6-12(26)8-10)13(21-15)9-3-1-5-11(25)7-9/h1-8,25-26H,(H4,19,20,22,23,24) |
| Inchi Key | UJIAQDJKSXQLIT-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)O)C2=NC3=C(N=C(N=C3N=C2C4=CC(=CC=C4)O)N)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/t26.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5851-T26-chemical-structure.png |