SMS121
SMS121 is a potent inhibitor of CD36 with a Kd value of 5.57 µM. It impairs fatty acid uptake, as well as the viability and proliferation of acute myeloid leukemia (AML) cells, indicating its potential as a future therapeutic agent against AML.
| Catalog Number | E5853 |
| Molecular Formula | C16H14F3N3O2S |
| Inchi | InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22) |
| Inchi Key | MJIHNNLFOKEZEW-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/sms121.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5853-SMS121-chemical-structure.png |