BIO-2007817
BIO-2007817 is a tetrahydropyrazolo-pyrazine and a positive allosteric modulator(PAM) that can act as a molecular glue to enhance the ability of pUb to activate Parkin with an EC50 of 150 nM. It can be used in research design of activators as therapeutics for Parkinson’s disease.
Catalog Number | E5771 |
Molecular Formula | C21H16F4N4O2S |
Inchi | InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30) |
Inchi Key | WXCXUHSOUPDCQV-UHFFFAOYSA-N |
SMILES | CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/bio-2007817.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5771-BIO-2007817-chemical-structure.png |