Chemical Phosphorylation Reagent I

This reagent can be used to create the 3′-phosphate by adding it as the first addition to the support. After ammonia deprotection the oligo will have the 3′-phosphate attached to the 2nd base added during synthesis. Both the support base and the CPR are cleaved. The DMT-group is removed during the ammonium hydroxide deprotection and thus is not available for poly-pak purification.

Catalog Number PIPB-0353
Research Area Phosphoramidites Series
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