Antihistamines, a potent anti-metamorphic agent with both tricyclic and piperidine structures, are characterized by both strong antagonism of histamine H1 receptors and inhibition of the release of allergic response mediators.

An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.

Antiarrhythmic drug, inhibits Na+ inward flow and promotes K+ outward flow in cardiomyocytes, shortens the action potential duration of Purdue fibers and the effective period of inactivity, delays intraventricular conduction, and raises the threshold of ventricular fibrillation. It is used for ventricular arrhythmia caused by various reasons.

Cerebral Metabolism Improver, a cerebral metabolism improvement drug, promotes glucose and amino acid metabolism in the brain, improves systemic anabolism, increases carotid blood flow, and improves cerebral blood flow.

Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide.

Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an insulin secretagogue. It is a N-sulfonylurea, […]

Hypoglycemic agents, used in patients with type II diabetes mellitus who are not satisfied with dietary control alone, especially those who are obese and with hyperinsulinemia, not only have a hypoglycemic effect, but may also have the effect of reducing weight and hyperinsulinemia.

Hypoglycemic agents, which inhibit hepatic glycogenolysis and gluconeogenesis by increasing portal insulin levels or by direct action on the liver, with decreased hepatic production and output of glucose, are rapidly absorbed orally and have a very high rate of protein binding.

It is a potent diuretic, mainly used to treat edema caused by heart, liver and kidney diseases.

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.