Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity.

A dopamine D2 antagonist that is used as an antiemetic.

It has a role as an antiemetic, a dopaminergic antagonist, a gastrointestinal drug, a xenobiotic and an environmental contaminant.

Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine bitartrate acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as […]

Nadroparin Calcium is a low molecular weight heparin (LMWH) composed of a heterogeneous mixture of sulfated polysaccharide glycosaminoglycan chains obtained by depolymerisation of porcine mucosal sodium heparin, extraction/purification and conversion to the calcium salt. Nadroparin binds to antithrombin III (ATIII) and inhibits the activity of activated factor X (factor Xa), thereby inhibiting the final common […]

Dalteparin Sodium is the sodium salt of a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, dalteparin binds to antithrombin and enhances the inhibition of Factor Xa. Compared to unfractionated heparins, the use of dalteparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia.

Heparin Lithium is a mucopolysaccharide that is used primarily as an anticoagulant. Heparin binds to antithrombin III and accelerates the rate of inhibition of coagulation proteases.

Heparin Calcium is a pharmacological agent aimed at the prevention and management of thrombus formation through potentiation of antithrombin III activity leading to the inhibition of multiple coagulation factors. Routinely employed in surgical settings, dialysis interventions, and in managing deep vein thrombosis and pulmonary embolism pathologies.

Vasodilator for the treatment of hypertension and angina pectoris. It is a calcium antagonist, inhibits transmembrane calcium ion inward flow in myocardial and vascular smooth muscle without altering blood calcium concentration, and is highly vasoselective.

Esomeprazole is a Proton Pump Inhibitor. The mechanism of action of esomeprazole is as a Proton Pump Inhibitor, and Cytochrome P450 2C19 Inhibitor.