Ionomycin calcium (SQ23377 calcium) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It is highly specific for divalent cations (Ca>Mg>Sr=Ba) and also promotes T cell activation and proliferation by inducing phosphoinositide hydrolysis and protein kinase C (PKC) activation, leading to IL-2 production and IL-2R expression.

Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.

BAY 2413555 is a first selective positive allosteric modulator of the muscarinic acetylcholine receptor (M2R) to restore cardiac autonomic balance. It also inhibits CYP2C8 and CYP2C9 with IC50 values of 17 µM and 13 µM, respectively.

BAY 2413555 is a first selective positive allosteric modulator of the muscarinic acetylcholine receptor (M2R) to restore cardiac autonomic balance. It also inhibits CYP2C8 and CYP2C9 with IC50 values of 17 µM and 13 µM, respectively.

BAY 2413555 is a first selective positive allosteric modulator of the muscarinic acetylcholine receptor (M2R) to restore cardiac autonomic balance. It also inhibits CYP2C8 and CYP2C9 with IC50 values of 17 µM and 13 µM, respectively.

SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.

SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.

5-Fluorouridine is a uridine analog and a potent inhibitor of ribozyme self-cleavage with an EC50 of 5.9 μM. It significantly inhibit ribozyme function via its covalent incorporation into the mRNA carrying the ribozyme sequences and can be used as used chemotherapeutic agent in cancer research.

SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.

SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.