G6PD activator AG1 is a small molecule activator of glucose-6-phosphate dehydrogenase (G6PDH) with an EC50 of 3.4 µM for G6PDH⁴⁵⁹ᴸ that enhances the activity of wild-type and mutant G6PD. It reduces oxidative stress in cells, zebrafish, and human erythrocytes, making it useful for research on G6PD enzymopathies.

G6PD activator AG1 is a small molecule activator of glucose-6-phosphate dehydrogenase (G6PDH) with an EC50 of 3.4 µM for G6PDH⁴⁵⁹ᴸ that enhances the activity of wild-type and mutant G6PD. It reduces oxidative stress in cells, zebrafish, and human erythrocytes, making it useful for research on G6PD enzymopathies.

G6PD activator AG1 is a small molecule activator of glucose-6-phosphate dehydrogenase (G6PDH) with an EC50 of 3.4 µM for G6PDH⁴⁵⁹ᴸ that enhances the activity of wild-type and mutant G6PD. It reduces oxidative stress in cells, zebrafish, and human erythrocytes, making it useful for research on G6PD enzymopathies.

GLPG3312 is a potent and selective inhibitor of pan-SIK, with an IC50 of 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3. It demonstrates anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models.

GLPG3312 is a potent and selective inhibitor of pan-SIK, with an IC50 of 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3. It demonstrates anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models.

GLPG3312 is a potent and selective inhibitor of pan-SIK, with an IC50 of 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3. It demonstrates anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models.

CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC₅₀ values of 144 nM for human recombinant monoacylglycerol lipase (MAGL), 90 nM for hormone-sensitive lipase (HSL), and 14 nM for fatty acid amide hydrolase (FAAH). It also inhibits cell growth in MCF-7, MB-231, COV318, OVCAR-3 cancer cell lines.

BTTAA is a Cu(I)-stabilizing ligand that enhances CuAAC reaction efficiency. It is highly effective for labeling and detecting azide-tagged glycoconjugates in Jurkat cells, zebrafish, and bacteria.

GLPG3312 is a potent and selective inhibitor of pan-SIK, with an IC50 of 2.0 nM for SIK1, 0.7 nM for SIK2, and 0.6 nM for SIK3. It demonstrates anti-inflammatory and immunoregulatory activities in vitro in human primary myeloid cells and in vivo in mouse models.

Ionomycin calcium (SQ23377 calcium) is a potent and selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. It is highly specific for divalent cations (Ca>Mg>Sr=Ba) and also promotes T cell activation and proliferation by inducing phosphoinositide hydrolysis and protein kinase C (PKC) activation, leading to IL-2 production and IL-2R expression.