Component of the 2’F-dNTP (2′-Fluorine-dNTP): 2′-F-dATP (2′-Fluoro-2′-Deoxyadenosine-5′-Triphosphate, Sodium Salt) 2′-F-dCTP (2′-Fluoro-2′-Deoxycytidine-5′-Triphosphate, Sodium Salt) 2′-F-dGTP (2′-Fluoro-2′-Deoxyguanosine-5′-Triphosphate, Sodium Salt) 2′-F-dUTP (2′-Fluoro-2′-Deoxyuridine-5′-Triphosphate, Sodium Salt)

5-OMe-UTP is a common chemical modification used in in vitro mRNA synthesis for incorporation into messenger RNA (mRNA) using T7 RNA polymerase, thereby reducing the activity and immunogenicity of the resulting mRNA

6-Thioguanosine (6-thio-G) has applications in ribozyme and siRNA research, as well as in RNA-protein interactions. The removal of the silyl protecting group without interfering with the sulfur is critical. This is removed1 cleanly by triethylamine trihydrofluoride in DMSO but t-butylammonium fluoride (TBAF) leads to degradation of the thio-nucleotide analogue and should not be used.