ZSH‐2208 is a RARγ-selective retinoic acid analogue that exhibits potent anti-tumor effects in oesophageal squamous cell carcinoma (ESCC). It inhibits ESCC tumour-repopulating cells (TRCs) by downregulating TNFAIP3, thereby suppressing proliferation and promoting apoptosis.

PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.

PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.

PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

CCR6 antagonist 1 is a potent antagonist of CCR6 that inhibits the CCL20/CCR6 axis. It can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).