SD-2301 is a potent and selective PROTAC-based STAT3 degrader that targets the VHL–cullin 2 complex, enhancing dendritic cell function and anti-tumor immunity. It synergizes with anti-PD-L1 therapy to robustly suppress tumor growth in vivo.

SD-2301 is a potent and selective PROTAC-based STAT3 degrader that targets the VHL–cullin 2 complex, enhancing dendritic cell function and anti-tumor immunity. It synergizes with anti-PD-L1 therapy to robustly suppress tumor growth in vivo.

SD-2301 is a potent and selective PROTAC-based STAT3 degrader that targets the VHL–cullin 2 complex, enhancing dendritic cell function and anti-tumor immunity. It synergizes with anti-PD-L1 therapy to robustly suppress tumor growth in vivo.

SD-2301 is a potent and selective PROTAC-based STAT3 degrader that targets the VHL–cullin 2 complex, enhancing dendritic cell function and anti-tumor immunity. It synergizes with anti-PD-L1 therapy to robustly suppress tumor growth in vivo.

CORM-401 is a water-soluble Carbon monoxide-releasing molecule that exhibits antioxidant and cytoprotective effects under oxidative stress conditions, including TNF-α/CHX and H₂O₂-induced damage. It induces nitric oxide production, activates the pentose phosphate pathway, and triggers distinct calcium signaling patterns, contributing to the regulation of endothelial function.

CORM-401 is a water-soluble Carbon monoxide-releasing molecule that exhibits antioxidant and cytoprotective effects under oxidative stress conditions, including TNF-α/CHX and H₂O₂-induced damage. It induces nitric oxide production, activates the pentose phosphate pathway, and triggers distinct calcium signaling patterns, contributing to the regulation of endothelial function.

Sulindac sulfide is a potent, reversible and noncompetitive inhibitor of γ42-secretase with an IC50 of 20.2 μM. It preferentially reduces Aβ42 generation, inhibits Aβ40 and Notch intracellular domain production, and can be used in Alzheimer’s disease research.

CORM-401 is a water-soluble Carbon monoxide-releasing molecule that exhibits antioxidant and cytoprotective effects under oxidative stress conditions, including TNF-α/CHX and H₂O₂-induced damage. It induces nitric oxide production, activates the pentose phosphate pathway, and triggers distinct calcium signaling patterns, contributing to the regulation of endothelial function.

CORM-401 is a water-soluble Carbon monoxide-releasing molecule that exhibits antioxidant and cytoprotective effects under oxidative stress conditions, including TNF-α/CHX and H₂O₂-induced damage. It induces nitric oxide production, activates the pentose phosphate pathway, and triggers distinct calcium signaling patterns, contributing to the regulation of endothelial function.