Sacubitril is a potent and orally active inhibitor of NEP (neprilysin) with an IC50 of 5 nM. It exhibits the potential to treat chronic heart failure with reduced ejection fraction.

N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water.

NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups.

Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids.

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit […]

5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.

n-Octyl β-D-glucopyranoside is a non-ionic glycolipid widely used in biochemical applications. It forms stable, hydrated prolate ellipsoid micelles and can inhibits cavitation-induced cell lysis in vitro.

Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).

D-α-tocopherol succinate (Vitamin E succinate) is an antioxidant tocopherol and a salt form of vitamin E that significantly reduces the cisplatin-induced increase of ROS and decreases cellular necrosis and late apoptosis, thereby inhibiting cisplatin-induced cytotoxicity in HEIOC1 cells. It also exhibits an anti-apoptotic effect.

5-ROX (5-Carboxy-X-rhodamine) is a rhodamine dye that exhibits strong fluorescence in aqueous buffer with an excitation maximum (λₑₓᵢₜ) at 580 nm (ε = 3.6 × 10⁴ M⁻¹ cm⁻¹) and an emission maximum (λₑₘᵢₜ) at 604 nm (ϕ = 0.94). It is highly photostable and widely used for biomolecular labeling and fluorescence-based detection.