Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity.

Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

Peroxidase, Horseradish is an archetypal haem-containing enzyme that uses hydrogen peroxide or alkyl peroxides to catalyze oxidative reactions, including the hydroxylation and polymerization of aromatic compounds. It is commonly used as a detection enzyme in biochemical assays like ELISA, Western blotting, and immunohistochemistry, due to its ability to produce strong colorimetric or chemiluminescent signals for […]

Ditolylguanidine (1,3-di-o-tolylguanidine) is a non-selective agonist of sigma receptor (σ receptor) with high affinity Ki values of 69 nM and 21 nM for σ1 and σ2 receptors, respectively. It effectively inhibits the growth of small cell lung cancer cells and can be used for the research of lung cancer.

Win 18446 is a bisdichloroacetyldiamines that inhibits ALDH1a2 enzyme activity in vitro with an IC50 of 0.3 μM. It also reversibly suppresses spermatogenesis by inhibiting testicular retinoic acid biosynthesis mediated by ALDH1A2.

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

EGNHS (EGS crosslinker) is a proteolytic targeting chimera (PROTAC) linker belonging to the alkyl/ether class, used in the synthesis of PROTAC molecules. It can form a cross-link between Lys232 and Lys241 of horseradish peroxidase C (HRP) and modify Lys174 without cross-linking.

c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune […]

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

Hydroxyphenyllactic acid is an antifungal metabolite.