Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research.

Tolrestat is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM.

Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option […]

Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents.

Rupatadine (UR-12592) is a potent, orally active and long-lasting dual antagonist of platelet-activating factor (PAF) and histamine (H1) with Ki of 0.55 μM and 0.1 μM, respectively. It exhibits anti-fibrosis effect and can be used in research on treatments for pulmonary fibrosis, allergic and inflammatory conditions involving both platelet-activating factor (PAF) and histamine.

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2).

Creatinine-d3 is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

Zinc Gluconate has the potential for the research of common cold, cancer, and a nutrition supplement as a food additive.

Ulinastatin (Uristatin) is the main inhibitor of a hydrolase protein and serine protease suppresses trypsin, chymotrypsin, and other pancreatic proteases. It can inhibit the production and release of inflammatory factors through mediating inflammatory pathways, while modulating apoptosis, enzyme activity, coagulation, and immune responses. It is effective in preventing and managing conditions like pancreatitis, cerebral edema, […]

Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.