Sulfanitran
25mg
| Purity Not Available
Selleck Chemicals
Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
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Nolatrexed dihydrochloride (AG 337) is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme, with a Ki of 11 nM for human thymidylate synthase. Nolatrexed dihydrochloride (AG 337) induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity.
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Atrasentan
5mg
| Purity Not Available
Selleck Chemicals
Atrasentan (ABT-627, (+)-A 127722, A-147627) is an antagonist of endothelin A (ETA) receptor with a Ki of 0.034 nM. It exhibits antitumor activity by inhibiting prostate cancer cell growth and inducing apoptotic cell death.
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Veratridine
5mg
| Purity Not Available
Selleck Chemicals
Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow.
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NSC-87877
5mg
| Purity Not Available
Selleck Chemicals
NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26).
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Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination.
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TFLLR-NH2
5mg
| Purity Not Available
Selleck Chemicals
TFLLR-NH2 is a selective and potent agonist of proteinase-activated receptor 1 (PAR1) with an EC50 of 1.9 μM. It has potential for researching early tumor metastasis and supports early antiplatelet therapy to suppress colorectal cancer spread and improve survival rates.
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Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.
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Terazosin
5mg
| Purity Not Available
Selleck Chemicals
Terazosin is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin works by relaxing blood vessels and the opening of the bladder. Terazosin has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment.
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