FMK 9a 1mg | Purity Not Available
Selleck Chemicals
FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.
More Information Supplier PageFMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.
More Information Supplier PageHydroxyphenyl Fluorescein is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein produces strong green fluorescence upon reaction with hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm.
More Information Supplier PageFT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis. FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
More Information Supplier PagePD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC12nnr5 cells, respectively .
More Information Supplier PageGadopentetic acid (Gd-DTPA) is a paramagnetic contrast agent. Gadopentetic acid commonly implemented by a bolus intravenous injection in Dynamic contrast-enhanced MRI (DCE-MRI) studies. Gadopentetic acid also can be used for the research of nephrogenic systemic fibrosis (NSF).
More Information Supplier PageDocebenone (AA 861) is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.
More Information Supplier PageRipasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
More Information Supplier PageSiramesine (Lu 28-179) is a potent agonist of sigma-2 receptor(σ1R) with an IC50 of 0.12 nM, exhibiting 140-fold selectivity over sigma-1 receptors. It shows strong anxiolytic effects and induces cancer cell death, highlighting its potential anticancer activity.
More Information Supplier PageCMS-121 is a quinolone derivative and an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC50 values of 7 nM and 200 nM, respectively. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidative and renoprotective activities.
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