Selleck Chemicals
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.
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R 59-022
1mg
| Purity Not Available
Selleck Chemicals
R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.
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L-Alanosine
1mg
| Purity Not Available
Selleck Chemicals
L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency.
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Selleck Chemicals
Ulixertinib hydrochloride (BVD-523 hydrochloride, VRT752271 hydrochloride) is a highly selective, ATP-competitive, and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of
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C527
5mg
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
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Selleck Chemicals
GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny).
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Selleck Chemicals
5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride; HMA) is a potent inhibitor of the Na⁺/H⁺ exchanger, lowering intracellular pH and inducing apoptosis. It also inhibits the HIV-1 Vpu virus ion channel and suppresses replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV-229E) in cultured L929 cells, with EC₅₀ values of 3.91 μM and 1.34 μM, respectively.
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Selenocystine
5mg
| Purity Not Available
Selleck Chemicals
Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment.
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Selleck Chemicals