Major apple (Malus domestica) allergen Mal d 1, a ribonuclease, is a heat-sensitive allergen and belongs to the protein class of pathogenesis-related (PR) proteins. The allergen shares homologous IgE epitopes with major birch pollen allergen Bet v 1 and Cor a 1 from hazelnut pollen.

Fel d 1 is a secretoglobin protein that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes. Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and […]

Dust mite allergy, also known as house dust allergy, is a sensitization and allergic reaction to the droppings of house dust mites. The allergy is common and can trigger allergic reactions such as asthma, eczema or itching. It is the manifestation of a parasitosis. The mite’s gut contains potent digestive enzymes (notably peptidase 1) that […]

Salmonella is a gram-negative, rod-shaped (bacillus) bacteria genus that belongs to the family Enterobacteriaceae. Salmonella contains two species: Salmonella enterica and Salmonella bongori. The type species is Salmonella enterica (S. enterica), which is widely found in warm-blood animals all over the world. Salmonella enterica can be further catalogued into 6 subspecies, with more than 2,500 […]

Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals which includes all higher animals from fishes to humans. During early embryonic development, retinoic acid generated in a specific region of the embryo helps determine position along […]

Triiodothyronine, C15H12I3NO4, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.

The thyroid hormones, triiodothyronine (T3) and its prohormone, thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. Iodine is necessary for the production of T3 and T4. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyroid tissue and will cause […]

DERP2 is a cause of an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. This protein and and Dermatophagoides farinae (Der f) are the major source of allergens for patients allergic to house dust mites (HDMs).

Doxycycline is a semisynthetic, tetracycline related bacteriostatic antibiotic that has been linked to rare instances of acute cholestatic liver injury.