The pyrrolobenzodiazepines (PBDs) are a class of antitumor antibiotics. PBDs are sequence-selective DNA minor-groove binding crosslinking agents originally discovered in Streptomyces species and are significantly more potent than systemic chemotherapeutic drugs. Pyrrolobenzodiazepines are potent inhibitors of nucleic acid synthesis because of their ability to recognize and bind to specific sequences of DNA and form a […]

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.Recently, gangliosides have been found to be highly important molecules in immunology. Natural and semisynthetic gangliosides are considered possible therapeutics for neurodegenerative disorders.

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.Ganglioside GT1b (d18:1/26:1(17Z)) is a GT1b ganglioside, A glycosphingolipid (ceramide and oligosaccharide) or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It […]

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.Ganglioside GT1b (d18:1/26:1(17Z)) is a GT1b ganglioside, A glycosphingolipid (ceramide and oligosaccharide) or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It […]

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.GT1a ganglioside is one of the minor neuronal gangliosides. Demonstrates high-affinity binding with amyloid beta-protein, useful as one of the markers of Alzheimer disease.Recently, gangliosides have been found to […]

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.GT1a ganglioside is one of the minor neuronal gangliosides. Demonstrates high-affinity binding with amyloid beta-protein, useful as one of the markers of Alzheimer disease.Recently, gangliosides have been found to […]