Selleck Chemicals
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications.
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Amiloride
25mg
| Purity Not Available
Selleck Chemicals
Amiloride (MK-870) is the first potent inhibitor of epithelial sodium channel (ENaC), inhibiting δβγ ENaC with an IC50 of 2.6 μM. It is also a typical blocker of PC2(TRPP2) channels and can be used in the research to study Autosomal dominant polycystic kidney disease (ADPKD).
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BAPTA
100mg
| Purity Not Available
Selleck Chemicals
BAPTA is a Ca²⁺ chelator and an inhibitor of phospholipase C (PLC) with an IC50 of 7.0 mM and exhibits high Ca²⁺ selectivity, minimal pH dependence, and a fast binding rate. Its rapid Ca²⁺ buffering capacity makes it ideal for studying Ca²⁺ release from intracellular stores or influx through Ca²⁺ channels.
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Selleck Chemicals
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice.
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Selleck Chemicals
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.
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Selleck Chemicals
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs).
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PIM447
1mg
| Purity Not Available
Selleck Chemicals
PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis.
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PRT-060318
5mg
| Purity Not Available
Selleck Chemicals
LUF6000
1mg
| Purity Not Available
Selleck Chemicals
LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect.
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Pyridoclax
5mg
| Purity Not Available
Selleck Chemicals