MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.GT1a ganglioside is one of the minor neuronal gangliosides. Demonstrates high-affinity binding with amyloid beta-protein, useful as one of the markers of Alzheimer disease.Recently, gangliosides have been found to […]

A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n-acetylneuraminic acid, NANA) linked on the sugar chain.GT1a ganglioside is one of the minor neuronal gangliosides. Demonstrates high-affinity binding with amyloid beta-protein, useful as one of the markers of Alzheimer disease.Recently, gangliosides have been found to […]

Gibberellic acids (Gibberellins) are naturally occurring plant hormones that are used as plant growth regulators to stimulate both cell division and elongation that affects leaves and stems.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

MMAD is a tubulin inhibitor and used to produce site-specific antibody drug conjugates.

DM1 (mertansine) is a thiol-containing derivative of maytansine. It binds to tubulin and inhibits the assembly of microtubules. DM1 is used to prepare antibody-drug conjugates, such as trastuzumab emtansine (abbreviated as T-DM1).

DM1 (mertansine) is a thiol-containing derivative of maytansine. It binds to tubulin and inhibits the assembly of microtubules. DM1 is used to prepare antibody-drug conjugates, such as trastuzumab emtansine (abbreviated as T-DM1).

Aldoxorubicin, also known as INNO-206 and Doxo-EMCH, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin with antineoplastic activity. INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, […]