Mature human FGF-10 is an approximately 20 kDa protein that contains a serine-rich region near its N-terminus (2, 3). It shares 93% and 96% amino acid sequence identity with mouse and rat FGF-10, respectively. Mature human FGF-10 is an approximately 20 kDa protein that contains a serine-rich region near its N-terminus (2, 3). It shares […]

Fibroblast growth factor 12 (FGF12) is a fibroblast growth factor homologous factor, a subset of the FGF superfamily. Human FGF-12 is synthesized as a 243 aa protein. In human Vascular smooth muscle cells (VSMCs), FGF12 expression was inhibited at the transcriptional level by platelet-derived growth factor-BB. FGF12 inhibited cell proliferation through the p53 pathway and […]

Fibroblast growth factor-9, is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted human FGF-9 is a 205-207 aa protein that lacks the N-terminal 1-3 aa and shares 98% sequence identity with mouse, rat, equine, porcine and bovine FGF-9. FGF-9 is an autocrine/paracrine growth factor considered to be important for the growth and […]

Fibroblast growth factor 10 (FGF-10) is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role in prenatal development, postnatal growth, and regeneration of various tissues by promoting cell proliferation and differentiation.FGF-10 is most closely related to KGF/FGF-7, and is expressed during development, preferentially in the adult […]

Human FGF-9 protein, also known as fibroblast growth factor 9, is a member of the fibroblast growth factor (FGF) family. It functions as a signaling molecule, regulating various cellular processes like cell proliferation, differentiation, and migration. FGF-9 protein plays a vital role in various physiological and pathological processes, making it an important focus of research […]

Fgf-8 is a member of the fibroblast growth factor (FGF) family that was initially identified as an androgen-inducible growth factor in a mammary carcinoma cell line. Fgf-8 is one of the key signaling molecules implicated in the initiation, outgrowth, and patterning of vertebrate limbs. The cloned 1.26-kb cDNA contained an open reading frame encoding 212 […]

Fibroblast growth factor-9, also called FGF-9, is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted human FGF-9 is a 205-207 aa protein that lacks the N-terminal 1-3 aa and shares 98% sequence identity with mouse, rat, equine, porcine and bovine FGF-9. In addition to FGF R3 (IIIb), FGF-9 binding to the IIIc […]

Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a member of the fibroblast growth factor (FGF) family. It plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Growth factor necessary for normal meristem morphogenesis and active in keratin-forming cells. May be a major paracrine […]

The fibroblast growth factor-4 (FGF-4) gene was identified as HST-1 gene from human stomach cancers and Kaposi’s sarcoma by a NIH3T3 transforming assay. FGF-4 has pleiotropic roles in many cell types and tissues, it is a mitogenic, angiogenic and survival factor, which is involved in cell proliferation and differentiation and in a variety of development […]

Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a member of the fibroblast growth factor (FGF) family. It plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Growth factor necessary for normal meristem morphogenesis and active in keratin-forming cells. May be a major paracrine […]