Carcinoid tumours are the most commonly occurring endocrine tumours. Although generally found in the gut wall, they also occur in the pancreas, rectum, ovary and lung. Carcinoid tumours typically contain numerous membrane-bound neurosecretory granules, which are composed of a variety of hormones and biogenic amines. One of the best characterized of these substances is serotonin. […]

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is produced primarily from androstenedione originating from the gonads or the adrenal cortex. In premenopausal women, more than 50% of the estrone is secreted by the ovaries. In prepubertal children, men and non supplemented postmenopausal women the major portion […]

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone (BAN), and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, 11-deoxycorticosterone can be understood as the 21-hydroxy- […]

Neomycin is an aminoglycoside broad spectrum antibiotic effective against both gram positive and gram negative bacteria. It interferes with protein synthesis in sensitive bacterial cells such as species of Proteus and Staphylococcus.

Hygromycin B is an antibiotic produced by the bacterium Streptomyces hygroscopicus. It is an aminoglycoside that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. Hygromycin B was originally developed in the 1950s for use with animals and is still added into swine and chicken feed as an anthelmintic or anti-worming agent (product […]