Antazoline hydrochloride(Phenazoline hydrochloride) is a first-generation antihistamine with anticholinergic properties and is commonly used to relieve nasal congestion and in eye drops. Antazoline hydrochloride exhibits a significant inhibitory effect on HBV DNA in the Huh7 cells, with an EC50 of 2.349 μmol/L.
More Information Supplier PageGilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.
More Information Supplier PageBosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
More Information Supplier PageGSK-843 (GSK’843) is a selective inhibitor of receptor-interacting protein kinase 3 (RIP3 or RIPK3) that binds to the RIP3 kinase domain with an IC50 of 8.6 nM and effectively inhibits its enzymatic activity with an IC50 of 6.5 nM.
More Information Supplier PageGSK-843 (GSK’843) is a selective inhibitor of receptor-interacting protein kinase 3 (RIP3 or RIPK3) that binds to the RIP3 kinase domain with an IC50 of 8.6 nM and effectively inhibits its enzymatic activity with an IC50 of 6.5 nM.
More Information Supplier PageDoxycycline HCl is a tetracycline antibiotic that commonly used to treat a variety of infections, and also a MMP inhibitor.
More Information Supplier PageHSP27 inhibitor J2 (J2) is an inhibitor of HSP27, which induces abnormal HSP27 dimers formation and suppresses the generation of HSP27 giant polymers, inhibiting the chaperone role of HSP27 and diminishing its cellular protective function. HSP27 inhibitor J2 (J2) enhances the antiproliferative activity of 17-AAG and increases the sensitivity of cisplatin-induced lung cancer cell growth […]
More Information Supplier PageHSP27 inhibitor J2 (J2) is an inhibitor of HSP27, which induces abnormal HSP27 dimers formation and suppresses the generation of HSP27 giant polymers, inhibiting the chaperone role of HSP27 and diminishing its cellular protective function. HSP27 inhibitor J2 (J2) enhances the antiproliferative activity of 17-AAG and increases the sensitivity of cisplatin-induced lung cancer cell growth […]
More Information Supplier PageHSP27 inhibitor J2 (J2) is an inhibitor of HSP27, which induces abnormal HSP27 dimers formation and suppresses the generation of HSP27 giant polymers, inhibiting the chaperone role of HSP27 and diminishing its cellular protective function. HSP27 inhibitor J2 (J2) enhances the antiproliferative activity of 17-AAG and increases the sensitivity of cisplatin-induced lung cancer cell growth […]
More Information Supplier PageReproxalap (ADX-102, NS-2) is a potent topically administered inhibitor of reactive aldehyde species (RASP).It exhibits anti-inflammatory and pain-relieving effects by covalently binding aldehydes, reducing eye inflammation, and showing clinical efficacy in dry eye disease, allergic conjunctivitis, and noninfectious anterior uveitis.
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