Methotrexate is in the class of medications called antimetabolites. The drug is used to treat severe psoriasis, rheumatoid arthritis and certain types of cancer. It works by slowing the proliferation of cells. Specifically, it inhibits the enzyme dihydrofolate reductase that is necessary for the synthesis of folic acid, which is required for the synthesis of […]

Progesterone 3-O-(carboxymethyl)oxime is an oxime O-ether consisting of progesterone having an O-(carboxymethyl)oxime group at the 3-position. It is an oxime O-ether, a 20-oxo steroid and a monocarboxylic acid. It derives from a progesterone.

UR-144 is a drug invented by Abbott Laboratories, that acts as a selective full agonist of the peripheral cannabinoid receptor CB2, but with much lower affinity for the psychoactive CB1 receptor.

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).

Cor a 1.0401 represents the major hazelnut allergen from Corylus avellana. This pathogenesis-related protein, PR-10, belongs to the family of Bet v1 homologues and is closely related to the major hazel pollen allergen Cor a 1.0103.

Nonspecific lipid transfer proteins (nsLTPs) are expressed throughout the plant tissues. They are characterized by a typical cysteine pattern forming disulfide bonds and are known as important allergens in fruits and tree nuts. Sensitization to nsLTP Cor a 8.0101 has been shown to be clearly more frequent among patients with hazelnut allergy in the Mediterranean […]

Mal d 3.0101, a non-specific lipid transfer protein (nsLTP), is a major apple (Malus domestica) allergen. LTPs are found mainly in aerial plant organs such as leaves, seeds, flowers, and fruit. The heat-stable protein is characterized by having resistance to pepsin hydrolysis.

Pen a 1.0101, a Tropomyosin, is the only major allergen in brown shrimp Penaeus aztecus. The panallergen is a highly conserved and soluble muscle protein characterized by an alpha-helical homodimeric, coiled-coil structure.