BMS-833923 50mg | Purity Not Available
Selleck Chemicals
BMS-833923 (XL139) is an orally bioavailable Smoothened antagonist. Phase 2.
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CFTRinh-172 10mg | Purity Not Available
Selleck Chemicals
CFTRinh-172 (CFTR inhibitor 172) is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.
More Information Supplier PageCFTRinh-172 50mg | Purity Not Available
Selleck Chemicals
CFTRinh-172 (CFTR inhibitor 172) is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.
More Information Supplier PageLGK-974 5mg | Purity Not Available
Selleck Chemicals
LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
More Information Supplier PageLGK-974 50mg | Purity Not Available
Selleck Chemicals
LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
More Information Supplier PageAZD1080 25mg | Purity Not Available
Selleck Chemicals
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.
More Information Supplier PageKPT-185 10mg | Purity Not Available
Selleck Chemicals
KPT-185 is a selective CRM1 inhibitor that induces growth inhibition and apoptosis in a panel of NHL cell lines with a median IC50 ~25 nM.
More Information Supplier PageSC144 5mg | Purity Not Available
Selleck Chemicals
SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.
More Information Supplier PageDZNeP (3-deazaneplanocin A) HCl 5mg | Purity Not Available
Selleck Chemicals
DZNeP (3-deazaneplanocin A) HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM in a cell-free assay.
More Information Supplier PageDZNeP (3-deazaneplanocin A) HCl 1mg | Purity Not Available
Selleck Chemicals
DZNeP (3-deazaneplanocin A) HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM in a cell-free assay.
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