GNF-5 100mg | Purity Not Available
Selleck Chemicals
GNF-5 is a selective and allosteric Bcr-Abl inhibitor with IC50 of 220 nM.
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XMD8-92 50mg | Purity Not Available
Selleck Chemicals
XMD8-92 is a potent and selective dual inhibitor of big map kinase (BMK1, ERK5) and bromodomain-containing proteins (BRDs, BET) with Kd of 80 nM and 170 nM for ERK5 and BRD4(1), respectively.
More Information Supplier PageFR 180204 25mg | Purity Not Available
Selleck Chemicals
FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively. It is 30-fold less potent against the related kinase p38α and failed to inhibit any kinases(MEK1, MKK4, IKKα, PKCα, Src, Syc, and PDGFα) at less than 30 μM.
More Information Supplier PageEntospletinib (GS-9973) 200mg | Purity Not Available
Selleck Chemicals
Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.
More Information Supplier PageHJC0350 50mg | Purity Not Available
Selleck Chemicals
HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1.
More Information Supplier PageHO-3867 25mg | Purity Not Available
Selleck Chemicals
HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. HO-3867 induces apoptosis.
More Information Supplier Page(S)-crizotinib 5mg | Purity Not Available
Selleck Chemicals
(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.
More Information Supplier Page(S)-crizotinib 20mg | Purity Not Available
Selleck Chemicals
(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.
More Information Supplier PageLDN-193189 2HCl 5mg | Purity Not Available
Selleck Chemicals
LDN-193189 (DM3189) 2HCl is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM […]
More Information Supplier PageML167 25mg | Purity Not Available
Selleck Chemicals
ML167 (CID 44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B.
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