Dalcetrapib (JTT-705) 5mg | Purity Not Available
Selleck Chemicals
Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. Phase 3.
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Varlitinib 5mg | Purity Not Available
Selleck Chemicals
Varlitinib (ARRY334543) is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.
More Information Supplier PageWortmannin 20mg | Purity Not Available
Selleck Chemicals
Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity.
More Information Supplier PageFimepinostat (CUDC-907) 5mg | Purity Not Available
Selleck Chemicals
CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.
More Information Supplier PageFimepinostat (CUDC-907) 10mM/1mL | Purity Not Available
Selleck Chemicals
CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.
More Information Supplier PageCanagliflozin (JNJ 28431754) 10mg | Purity Not Available
Selleck Chemicals
Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
More Information Supplier PageCanagliflozin (JNJ 28431754) 10mM/1mL | Purity Not Available
Selleck Chemicals
Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
More Information Supplier PageNVP-BVU972 5mg | Purity Not Available
Selleck Chemicals
NVP-BVU972 is a selective and potent Met (c-Met) inhibitor with IC50 of 14 nM.
More Information Supplier PageAlectinib 5mg | Purity Not Available
Selleck Chemicals
Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.
More Information Supplier PageAlectinib 50mg | Purity Not Available
Selleck Chemicals
Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.
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