HA14-1 50mg | Purity Not Available
Selleck Chemicals
HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.
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Nutlin-3 5mg | Purity Not Available
Selleck Chemicals
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
More Information Supplier PageOlaparib (AZD2281) 10mM/1mL | Purity Not Available
Selleck Chemicals
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
More Information Supplier PageOlaparib (AZD2281) 100mg | Purity Not Available
Selleck Chemicals
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
More Information Supplier PageOlaparib (AZD2281) 25mg | Purity Not Available
Selleck Chemicals
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
More Information Supplier PageOlaparib (AZD2281) 10mg | Purity Not Available
Selleck Chemicals
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
More Information Supplier PageObatoclax Mesylate (GX15-070) 10mM/1mL | Purity Not Available
Selleck Chemicals
Obatoclax Mesylate (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM in a cell-free assay, can assist in overcoming MCL-1 mediated resistance to apoptosis.
More Information Supplier PageNutlin-3 25mg | Purity Not Available
Selleck Chemicals
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
More Information Supplier PageNutlin-3 100mg | Purity Not Available
Selleck Chemicals
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
More Information Supplier PageNutlin-3 10mM/1mL | Purity Not Available
Selleck Chemicals
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
More Information Supplier Page