Nelarabine 10mM/1mL | Purity Not Available
Selleck Chemicals
Nelarabine (506U78,Arranon) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
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Decitabine 10mM/1mL | Purity Not Available
Selleck Chemicals
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
More Information Supplier PageMelatonin 10mM/1mL | Purity Not Available
Selleck Chemicals
Melatonin is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.
More Information Supplier PagePIK-75 HCl 10mg | Purity Not Available
Selleck Chemicals
PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
More Information Supplier PageBisoprolol fumarate 25mg | Purity Not Available
Selleck Chemicals
Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.
More Information Supplier PageTivozanib 50mg | Purity Not Available
Selleck Chemicals
Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
More Information Supplier PageTivozanib 5mg | Purity Not Available
Selleck Chemicals
Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
More Information Supplier PageDoxorubicin (DOX) HCl 10mg | Purity Not Available
Selleck Chemicals
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended […]
More Information Supplier PageExemestane 50mg | Purity Not Available
Selleck Chemicals
Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.
More Information Supplier PageCladribine 10mM/1mL | Purity Not Available
Selleck Chemicals
Cladribine is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.
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