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LY2886721 10mM/1mL  | Purity Not Available

Selleck Chemicals

LY2886721 is a BACE inhibitor used for the treatment of Alzheimer’s Disease. Phase 1/2.

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Tebipenem Pivoxil 50mg  | Purity Not Available

Selleck Chemicals

Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.

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Almorexant HCl 5mg  | Purity Not Available

Selleck Chemicals

Almorexant HCl (ACT-078573) is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.

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RAF265 (CHIR-265) 5mg  | Purity Not Available

Selleck Chemicals

RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.

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RAF265 (CHIR-265) 10mM/1mL  | Purity Not Available

Selleck Chemicals

RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.

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AZD1480 50mg  | Purity Not Available

Selleck Chemicals

AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.

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AZD1480 5mg  | Purity Not Available

Selleck Chemicals

AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.

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Sonidegib 10mM/1mL  | Purity Not Available

Selleck Chemicals

Sonidegib is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.

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