Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.
More Information Supplier PageBuflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease; A nonselective alpha adrenergic receptor inhibitor.
More Information Supplier PageQuinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.
More Information Supplier PageTrazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
More Information Supplier PageBrompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.
More Information Supplier PageDMF (Dimethyl Fumarate) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression.
More Information Supplier PagePioglitazone is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.
More Information Supplier PagePioglitazone is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.
More Information Supplier PageTolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.
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