Search Results

WZ811 10mM/1mL  | Purity Not Available

Selleck Chemicals

WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.

More Information Supplier Page

PF-477736 10mM/1mL  | Purity Not Available

Selleck Chemicals

PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.

More Information Supplier Page

Ki16198 5mg  | Purity Not Available

Selleck Chemicals

Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.

More Information Supplier Page

Pirfenidone 50mg  | Purity Not Available

Selleck Chemicals

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.

More Information Supplier Page

Tempol 100mg  | Purity Not Available

Selleck Chemicals

Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.

More Information Supplier Page

Go 6983 10mM/1mL  | Purity Not Available

Selleck Chemicals

Go 6983 (GOE 6983, Gö 6983) is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKCζ and inactive to PKCμ.

More Information Supplier Page

WZ811 50mg  | Purity Not Available

Selleck Chemicals

WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.

More Information Supplier Page

BAY 11-7082 50mg  | Purity Not Available

Selleck Chemicals

BAY 11-7082 (BAY 11-7821) is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.

More Information Supplier Page