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Apremilast 10mM/1mL  | Purity Not Available

Selleck Chemicals

Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.

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Necrostatin-1 100mg  | Purity Not Available

Selleck Chemicals

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.

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UPF 1069 10mg  | Purity Not Available

Selleck Chemicals

UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM. It is ~27-fold selective against PARP1.

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UPF 1069 50mg  | Purity Not Available

Selleck Chemicals

UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM. It is ~27-fold selective against PARP1.

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Empagliflozin 25mg  | Purity Not Available

Selleck Chemicals

Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.

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Empagliflozin 5mg  | Purity Not Available

Selleck Chemicals

Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.

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Empagliflozin 10mM/1mL  | Purity Not Available

Selleck Chemicals

Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.

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GSK3787 50mg  | Purity Not Available

Selleck Chemicals

GSK3787 is a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ.

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U73122 5mg  | Purity Not Available

Selleck Chemicals

U73122 is a potent phospholipase C (PLC) inhibitor, which reduces agonist-induced Ca2+ increases in platelets and PMN. U73122 potently inhibits human 5-lipoxygenase (5-LO).

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