Megestrol Acetate 50mg | Purity Not Available
Selleck Chemicals
Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.
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Mercaptopurine (6-MP) 50mg | Purity Not Available
Selleck Chemicals
Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
More Information Supplier PageMercaptopurine (6-MP) 10mM/1mL | Purity Not Available
Selleck Chemicals
Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
More Information Supplier PageZoledronic acid (Zoledronate) 25mg | Purity Not Available
Selleck Chemicals
Zoledronic acid (Zoledronate), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.
More Information Supplier PageZoledronic acid (Zoledronate) 100mg | Purity Not Available
Selleck Chemicals
Zoledronic acid (Zoledronate), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.
More Information Supplier PageKi16425 5mg | Purity Not Available
Selleck Chemicals
Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM in RH7777 cell lines, respectively, shows no activity at LPA4, LPA5, LPA6.
More Information Supplier PageAMG-208 10mg | Purity Not Available
Selleck Chemicals
AMG 208 is a highly selective dual c-Met and RON inhibitor with IC50 of 9 nM for c-Met.
More Information Supplier PageCamptothecin (CPT) 100mg | Purity Not Available
Selleck Chemicals
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
More Information Supplier PageCelastrol 50mg | Purity Not Available
Selleck Chemicals
Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson’s disease through activating mitophagy.
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